Syllabus

Science Prerequisites for Health Professionals

BIOL 1030: Pathophysiology: Mechanisms of Diseases – Spring 2019

Credits - 4

Description

Overview

Pathophysiology is the study of disordered physiological processes associated with disease.

This course is an introduction to pathophysiology designed especially to meet the needs of students preparing for careers in the health professions – for example, Physician Assistant, Pharmacy,  Medicine, Nursing, and Dental Hygiene.

This course focuses on the changes in cellular and systemic physiology that occur in prevalent or important medical conditions. At the cellular level we will cover the responses to tissue injury, abnormal cell growth and the immune system. From there we will investigate the physiological basis of problems associated with most of the major organ systems. In each case we will discuss the effect upon whole body homeostasis. This course will build on prior knowledge of anatomy and physiology as we explore body functions in altered health conditions. The primary teaching methods will be online audio lectures with slides, textbook reading, and online assessments, supplemented with multi-media resources including interactive tutorials and animations.

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Study Lounge

The Study Lounge Discussion Board is a designated support forum in which students may engage with each other and grapple with course content. Feel free to post questions, seek clarification, and support each other, but be mindful of UNE’s Academic Integrity Policy.

Your instructor will monitor this forum. However, if you are seeking specific and timely answers to questions about content-matter or your personal grades, please contact your instructor via course messages. For questions about course materials, program policy, and how to navigate and proceed through the course, please contact your Student Support Specialist through the course messaging system.

Materials

  • Grossman SP, C. Porth’s Pathophysiology: Concepts of altered health states. 9th ed. Wolters Kluwer Health/Lippincott Williams & Wilkins; 2014.
    • NOTE: The recently released 10th edition has differently organized chapters. If you are using the 10th edition, use this table to recognize what readings are required week by week.
  • Hands-on Learning Lab Kit: LP-2981-AP-01

    The kits MUST BE ORDERED IMMEDIATELY UPON ENROLLMENT in order to ensure materials are on hand for the start of the course. Note: Kits can take 5–7 business days to arrive. Once you receive the kit and have been given a code by your instructor, please use these directions for registration.

  1. Go to www.holscience.com
  2. Click on “STUDENTS ORDER HERE”
  3. Click on the green “YES”
  4. ENTER Login: C000384
  5. ENTER Password: labpaq
  6. Choose LP-2981-AP-01
  7. Review the HOL Return and Refund Policy

 

For the best HOL experience, please use Chrome, Firefox or Safari

Learning Objectives and Outcomes

Program Outcomes

In lecture courses, students should be able to:

  1. Communicate scientific concepts and information clearly.
  2. Illustrate fundamental laws, theories, and principles of scientific disciplines.
  3. Apply knowledge and critical thinking skills to scientific problems.

Course Objectives

Upon successful completion of the course, students will be able to:

  • Explain the concept, classification, etiology of disease states and imbalances. 

  • Analyze how health deviations alter normal physiology. 

  • Describe the alterations in cells, tissues, and organs that occur with disease and how they affect the body functions.
  • Describe the clinical manifestations of diseases and the most commonly used tests and procedures to diagnose them. 

  • Discuss the most frequent complications of diseases and their prognoses.
  • Set the pathophysiological foundation for treatments.  

SELF PACED DESIGN

On the course start date, students will have access to orientation. This must be completed to be able to gain access to the first module in the course. Students must complete the first module to gain access to the next one. We recommend that students spend about 15 hours per week to complete a course in 16 weeks. When trying to complete the course in less than 16 weeks, we typically see students do this successfully within 12-14 weeks. Instructors will be timely in grading and feedback, but it will not be instant.

Assignments

Lectures and Assignments

This course requires the following prerequisite prior to registering for the course: Successful completion of Anatomy and Physiology (200 level preferred) or equivalent with permission of the instructors.

Students are expected to log in at least three times a week for the entire course. All required assignments and assessments will be posted inside the UNE Blackboard course module. Each module will have learning objectives, lectures, assigned reading, online activities, and self assessments, followed by a weekly quiz. 

Examination and Grading Information  

Midterm and Final Exam

Exams will be taken through ProctorU (see below), and will consist of approximately 50 multiple-choice type questions (each) with seventy-five minutes (each) allowed for completion. The Midterm exam covers material from Weeks 1-7; the final exam covers Weeks 9-15. These tests are closed book and no notes are permitted. Back-tracking is permitted on these exams. No re-takes are allowed, except under extraordinary conditions (e.g., documented technical problem).

14 Weekly Quizzes

The quiz for each week (except Weeks 8 and 16) will consist of approximately 10 multiple-choice and multiple-answer type questions. Quizzes will be taken through Blackboard, and may be taken open book, but will be timed, with fifteen minutes allowed for completion and no backtracking.

3 Student Presentations

There are three recorded presentations required in the course, due in Weeks 2, 9 and 15. 

For Weeks 2 and 9, you will be asked to record 5-minute presentations, without using slides, in which you need to exhibit deep enough understanding of specified concepts and terms to explain those concepts and terms orally. Please go to the course week in which each is due and refer to 

In Week 15, you will be asked to record a presentation with slides on a disease of your own choosing. You will need to research the disease and describe certain details about the syndrome in your presentation—see detailed instructions for list of details you are required to cover.

Please go to the course week in which each of the presentations is due to find the detailed instructions for these assignments, and study them carefully.

Presentation Rubric:

 

Criteria

Proficient

Competent

Novice

Not Evident

Coverage of concepts

Presentation touches upon all concepts/details listed in the instructions for the student to cover.

One or two concepts/details listed in the assignment instructions are not covered in the presentation.  

More than two of the concepts / details in the instructions for the assignment go un-addressed.

 

Accuracy

Student accurately describes all concepts/details and aspects that he or she touches upon over the course of the presentation.

One or two concepts/details are incorrectly described.

Student regularly incorrect.

 

Presentation Mechanics

Student is able to clearly describe subject-matter concepts and, where directed, cleanly integrate media (such as slides) into presentation.

If slides are not used, student does not need to refer to notes.

Ideas are organized.

Any sources of information are clearly cited.

Otherwise solid presentation is occasionally undermined by lack of focus or disorganization.

If slides are not used, student rarely refers to notes.

Any sources of information are cited.

Presentation disorganized or regularly unclear.

Student regularly pauses to refer to notes.

Sources of information go uncited.

Slides (if used) have errors in them and/or are disorganized.

 

Case Studies / Quizzes

There are 6 Case Studies with associated quizzes in the course. These case studies portray a patient-provider care situation, and you will be prompted to answer Matching questions using details from the case studies to inform your answers. 

Discussions

There are several discussions in the course, in which you will be expected to draw from the course material, and sometimes material from outside the course, in order to post and participate. 

Discussion rubric:

Criteria

Proficient

Competent

Novice

Not Evident

Communication of Scientific Concepts and Information

Post and responses clearly demonstrate mastery of the course concepts and information, the ability to communicate complex ideas through writing, and relevance to the prompt or question.

Post and responses show general accuracy about course concepts, some challenges in communicating complex ideas through writing, and are largely relevant to the prompt or question.

Post and responses show some potentially serious misunderstandings of course concepts, significant challenges in communicating complex ideas through writing, or are only tangentially relevant to the prompt or question.

Post and/or responses show no clear understanding of course concepts, disorganized or incoherent writing, or are irrelevant to the prompt or question.

Critical and Innovative Thinking

Post and responses are characterized by clarity of argument, depth of insight into course content, and ability to use course content and ideas to create new knowledge or solve real-world problems.

Post and responses present an argument, show some insight into course content, and attempt to use course content to create new knowledge or solve real-world problems.

Post and responses lack a clear argument, show little insight into course content, or do not make a sincere attempt to create new knowledge or solve real-world problems.

Post and/or responses do not demonstrate critical or innovative thinking in response to the prompt, question, or classmates’ posts.

Response to Another Student #1

Provided response to classmate’s post that shows substantive and insightful engagement with the original post, and that facilitates ongoing discussion.

Provided response to classmate’s post that shows some engagement with the original post, and that facilitates ongoing discussion.

Provided response to classmate’s post that is generic (providing little detail or explanation) or that otherwise does not engage substantively with the original post.

Did not respond to classmate’s post.
Response to Another Student #2

 

Provided response to classmate’s post that shows substantive and insightful engagement with the original post, and that facilitates ongoing discussion.

Provided response to classmate’s post that shows some engagement with the original post, and that facilitates ongoing discussion.

Provided response to classmate’s post that is generic (providing little detail or explanation) or that otherwise does not engage substantively with the original post.

Did not respond to classmate’s post.
Writing Skill, Grammar, and AMA Formatting

Post and responses are free of grammar and spelling errors. Writing shows command of standard written English conventions. All sources are cited with AMA formatting.

Some errors in grammar or spelling, but errors do not make the meaning of the post or responses unclear. Sources used are cited, though potentially with minor errors in AMA formatting.

Regular, recurring errors that make the original post and/or responses confusing at times to the reader, or sources are not cited or are incorrectly cited using AMA formatting.

Writing was extremely difficult to follow due to regular, recurring grammatical or spelling errors, or garbled sentence structure.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

AssignmentPercentage Grade Value
Weekly Quizzes (14, each worth 1% of the final grade)14%
Case Studies (6, each worth 2% of the final grade)12%
Discussions (5, each worth 1.2% of the final grade)6%
Student Presentations (3, worth 4%, 4% and 5% of the final grade)13%
Dissection Labs (4, each worth 2.5% of the final grade)10%
Midterm20%
Final25%
Total100%

Grade Scale

Grade Points Grade Point Average (GPA)
A 94 – 100% 4.00
A- 90 – 93% 3.75
B+ 87 – 89% 3.50
B 84 – 86% 3.00
B- 80 – 83% 2.75
C+ 77 – 79% 2.50
C 74 – 76% 2.00
C- 70 – 73% 1.75
D 64 – 69% 1.00
F 00 – 63% 0.00

Schedule

Course Outline

This course is designed to be completed in a 16-week period, which breaks down to one module per week for 14 weeks and two exam weeks (midterm and final). One week in this online course is equivalent to 200 minutes of lecture in a traditional classroom setting. The general rule of studying for science courses is to spend 3 hours studying for every hour that you are in class. Therefore, the suggested study time for each module is 12 hours above and beyond the time it takes to listen to the lecture. Please refer to the schedule below for the order of topics.

Weeks

Topics and Notable Assignments

Text Readings**

1

Health and Disease, Stress and Adaptation

  • Discussion: What is Pathophysiology?
  • Week 1 Case Study
  • Week 1 Quiz

Chapters 1 and 9

2

Cellular Adaptation, Injury, and Death. Neoplasia.

  • Short Video Presentation – Basic Concepts
  • Week 2 Case Study
  • Week 2 Quiz

Chapters 5 and 8

3

Mechanisms of Infectious Diseases. Innate and Adaptive Immunity. Inflammation, Tissue Repair, and Wound Healing. Disorders of the Immune Response.

  • Week 3 Case Study
  • Week 3 Quiz

Chapters 12, 13, 14, 15 and 16

4

Disorders of Motor Function. Disorders of Brain Function. Disorders of memory.

  • Sheep Brain Dissection
  • Week 4 Quiz

Chapters 19, 20 and 22

5

Disorders of Visual Function. Disorders of hearing and Vestibular Function.

  • Dissection of Cow Eye
  • Week 5 Quiz

Chapters 23 and 24

6

Disorders of the hemostasis. Disorders of Red Blood Cells. Disorders of White Blood Cells and Lymphoid Tissues

  • Discussion: Homeostasis
  • Week 6 Quiz

Chapters 26, 27 and 28

7

Disorders of blood flow in the systemic circulation. Disorders of blood pressure regulation. Disorders of cardiac Function. Disorders of cardiac conduction and rhythm. Heart failure and circulatory shock.

  • Dissection of Sheep’s Heart
  • Week 7 Quiz

Chapters 30, 31, 32, 33, 34

8

MIDTERM EXAM

  • Discussion: Etiology of disease
 

9

Respiratory tract Infections, neoplasms, and childhood disorders. Disorders of ventilation and gas exchange.

  • Short Video Presentation – Syndrome
  • Week 9 Quiz

Chapters 36 and 37

10

Disorders of fluids and electrolyte balance. Disorders of Acid-Base balance. Disorders of renal function. Acute renal injury and chronic kidney disease. Disorders of the bladder and urinary tract.

  • Dissection of Sheep’s Kidney
  • Week 10 Quiz

Chapters 39, 40, 41, 42 and 43

11

Disorders of the gastrointestinal function. Disorders of hepatobiliary and exocrine pancreas function.

  • Week 11 Case Study
  • Week 11 Quiz

Chapters 45 and 46

12

Disorders of endocrine control of growth and metabolism. Diabetes mellitus and the metabolic syndrome.

  • Discussion: The Endocrine System
  • Week 12 Quiz

Chapters 49 and 50

13

Disorders of the male genitourinary system. Disorders of the female genitourinary system.

  • Week 13 Case Study
  • Week 13 Quiz

Chapters 52 and 54

14

Disorders of the musculoskeletal function: Trauma, Infection, Neoplasms, Developmental and metabolic disorders, Rheumatic disorders.

  • Week 14 Case Study
  • Week 14 Quiz

Chapters 57, 58 and 59

15

Disorders of skin integrity and function.

  • Short Video Presentation – Final Presentation on Disease of Choice
  • Week 15 Quiz

Chapter 61

16

FINAL EXAM

  • Discussion – Reflection on concept of pathophysiology
 

** Please go to individual weeks in Blackboard for detailed instructions.

Student Resources

Instructor and Support Contact Information

Contact: Contact via Blackboard course messaging system. It will help us track messages better and get back to you promptly.

Office hours: by appointment

Further Assistance

Your student support specialist monitors course progression and provides assistance or guidance when needed. They can assist questions regarding ordering course materials, University policies, billing, navigating the course in Blackboard, and more.

Online Student Support

Your Student Support Specialist is a resource for you - they will monitor course progression and provide assistance or guidance when needed. Please don’t hesitate to contact them for assistance, including, but not limited to course planning, course materials, billing, current problems or issues in a course, technology concerns, or personal emergencies.

Questions? Visit the Student Support Science Prerequisites page

Online Peer Support

Togetherall is a 24/7 communication and emotional support platform monitored by trained clinicians. It’s a safe place online to get things off your chest, have conversations, express yourself creatively, and learn how to manage your mental health. If sharing isn’t your thing, Togetherall has other tools and courses to help you look after yourself with plenty of resources to explore. Whether you’re struggling to cope, feeling low, or just need a place to talk, Togetherall can help you explore your feelings in a safe supportive environment. You can join Togetherall using your UNE email address.

Instructor and Support Contact Information

Check Brightspace for specific instructor and support specialist contact information.

Student Lounge

The Student Lounge Discussion Forum is a designated support forum in which students may engage with each other and grapple with course content. Feel free to post questions, seek clarification, and support each other, but be mindful of UNE's Academic Integrity Policy.

Your instructor will monitor this forum. However, if you are seeking specific and timely answers to questions about course content or your personal grades, please contact your instructor via course messages. For questions about course materials, program policy, and how to navigate and proceed through the course, please contact your Student Service Advisor through the Student Portal.

Accommodations

Any student who would like to request, or ask any questions regarding, academic adjustments or accommodations must contact the Student Access Center at (207) 221-4438 or pcstudentaccess@une.edu. Student Access Center staff will evaluate the student's documentation and determine eligibility of accommodation(s) through the Student Access Center registration procedure.

Online Peer Support

Togetherall is a 24/7 communication and emotional support platform monitored by trained clinicians. It’s a safe place online to get things off your chest, have conversations, express yourself creatively, and learn how to manage your mental health. If sharing isn’t your thing, Togetherall has other tools and courses to help you look after yourself with plenty of resources to explore. Whether you’re struggling to cope, feeling low, or just need a place to talk, Togetherall can help you explore your feelings in a safe supportive environment. You can join Togetherall using your UNE email address.

Information Technology Services (ITS)

Students should notify their Student Support Specialist and instructor in the event of a problem relating to a course. This notification should occur promptly and proactively to support timely resolution.

ITS Contact: Toll-Free Help Desk 24 hours/7 days per week at 1-877-518-4673.

Career Ready Program

The College of Professional Studies supports its online students and alumni in their career journey!

The Career Ready Program provides tools and resources to help students explore and hone in on their career goals, search for jobs, create and improve professional documents, build professional network, learn interview skills, grow as a professional, and more. Come back often, at any time, as you move through your journey from career readiness as a student to career growth, satisfaction, and success as alumni.

Policies

Proctored Examinations

The University of New England has contracted with ProctorU to provide students with the most convenient online exam proctoring system. This system provides a simple, no cost to the student, secure, online proctor for exams and allows the student to take all the exams at home and on their own schedule.

Upon enrollment into the course, each student will register with ProctorU and establish a login name and password. This will give the student access to all of ProctorU's services. When ready, students will schedule each of their proctored exams with ProctorU. Exams must be scheduled at least 72 hours in advance to avoid fees. Prior to taking their exams, students must be sure that they have downloaded the ProctorU Chrome or Firefox extension and are using the most current version of Chrome or Firefox. They must also be sure their testing site's connection meets the minimum requirements by using ProctorU's "Test It Out" utility.

Upon the exam day and hour, students will log in to ProctorU and click on "exams". After following the procedures outlined at ProctorU's web site, the student will log in to Brightspace and locate their correct exam. The proctor will then allow student access to that exam.

Students must use ProctorU and must follow all proctoring requirements for their exams to be credited.

Proctored exams are not available for review at any time. You will not be able to see the questions, nor the answers you've given, after completing the exams. Please contact your instructor for specific feedback.

Course Discussions

Discussion board assignments cover interesting current events or materials related to this course that contribute to a deeper understanding of key concepts and allow you to interact with your classmates and the instructor. Each assignment may require you to conduct internet research, read additional materials (a short journal or magazine article), visit a specific webpage, AND/OR view a short video prior to writing a response following the specific guidelines in the assignment.

To earn full credit: you will need to post a response to the discussion topic, respond to the original posts of at least two other students, and then contribute meaningfully to an ongoing discussion. You will need to post your initial response before you will see any posts from your classmates. Please keep in mind that only this initial response is included in your assignment grade, so make sure you have followed all of the guidelines and written a complete response prior to submitting the post. For special cases where one or two students are accelerating faster through the course, the instructor will participate in the discussion so that everyone has the opportunity to interact.

Please see Brightspace for a full description, along with specific guidelines, for each assignment. Discussion board assignments should be completed, along with all other assignments in the course, in the order that they appear. Due to the course design, you may be unable to take a proctored exam if you do not complete all assignments that appear prior to that exam.

Please also refer to the Grading Policy/Grade Breakdown section of the syllabus to learn the percentage of your grade that each discussion board assignment is worth.

Technology Requirements

Please review the technical requirements for UNE Online Programs: Technical Requirements

Course Length

A schedule of lectures and assignments is included in this syllabus. This is, however a self-paced course and you can complete the course in less time.

  1. Courses in the SPHP program are equivalent to one-semester courses designed to be completed in 16 weeks
  2. Enrollment in the course begins the day your section opens which is listed in the Academic Calendar found on the Student Success Portal.
  3. Course start and end dates are in respect to Eastern Time.

Withdrawal and Refund Policies

Please visit the enrollment page to review the withdrawal and refund policies.

Grade Policy

Students are expected to attempt and complete all graded assignments and proctored exams by the end date of the course. View the incomplete grade policy..

Transcripts

Due to the Family Educational Rights and Privacy Act, only the student may request official transcripts. This may be done online by going to the University of New England Registrar website and following the directions on the page.

To view your unofficial UNE student transcript:

  1. Log into uonline at http://uonline.une.edu
  2. Select Student Services
  3. Select Student Records
  4. Select Academic Transcript

To request your official UNE student transcript:

Please review your Unofficial Transcript prior to requesting an Official Transcript.

  1. Log into uonline at http://uonline.une.edu
  2. Select Student Services
  3. Select Student Records
  4. Select Request Printed/Official Transcript
  5. Follow the prompts

After you click Submit Request, your official transcript will be put into the queue to be printed in the Registrar's Office.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable.

Academic dishonesty includes, but is not limited to the following:

  1. Cheating, copying, or the offering or receiving of unauthorized assistance or information.
  2. Fabrication or falsification of data, results, or sources for papers or reports.
  3. Action which destroys or alters the work of another student.
  4. Multiple submission of the same paper or report for assignments in more than one course without permission of each instructor.
  5. Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.