Syllabus

Post Baccalaureate in Pre-Health

CHEM 1050: Biochemistry – Summer Session – 6 Weeks

Credits - 4

Description

This online course serves as an introduction to the fundamental principles of biochemistry, providing students with a comprehensive understanding of the chemical processes that occur within living organisms.  Students will explore the structure, function, and regulation of biological molecules, including proteins, lipids, and carbohydrates.  This course will cover topics including metabolic pathways, enzymology, metabolism, and the integration of biochemical processes in cellular functions. 

Topics Covered:

  1. Structure and functions of proteins and enzymes.
  2. Enzymes: kinetics, mechanism, and regulation
  3. Bioenergetics
  4. Metabolism of carbohydrates and lipids

Materials

Rodwell VW, Bender DA, Botham KM, Kennelly PJ, Weil PA. Harper’s Illustrated Biochemistry. 31st ed. McGraw-Hill Education LLC; 2018.  (UNE Library Access)

Learning Objectives and Outcomes

Upon the completion of this course the student will be able to:

  • Appreciate the scope of biochemistry and its central role in the life sciences.
  • Explain the physical properties of water.
  • Define and apply pH, pKa, pI, and K.
  • Provide examples of how each type of R group of the amino acids contributes to their chemical properties.
  • Evaluate how enzymes facilitate chemical reactions and the necessity of metabolic cofactors or vitamins in these reactions; relate how enzyme activities and concentrations may be used in clinical diagnosis.
  • Assess the different mechanisms by which hormones signal and influence metabolic pathways allowing for homeostasis within the body.
  • Describe the metabolism of carbohydrates (glucose, galactose and fructose) and their role in generating ATP for the cell.
  • Demonstrate an understanding of lipid metabolism, transport and storage in the fed and fasted conditions.
  • Relate how amino acids are used in the processes of protein synthesis, precursors for synthesis of necessary compounds and as substrates for glucose production; determine the role of the urea cycle in coordinating amino acid catabolism and nitrogen disposal.
  • Interpret the role and regulation of the metabolism of proteins, carbohydrates, and lipids in normal physiological conditions and the changes that may occur.

SELF PACED DESIGN

On the course start date, students will have access to orientation. This must be completed to be able to gain access to the first module in the course. Students must complete the first module to gain access to the next one. We recommend that students spend about 15 hours per week to complete a course in 16 weeks. When trying to complete the course in less than 16 weeks, we typically see students do this successfully within 12-14 weeks. Instructors will be timely in grading and feedback, but it will not be instant.

Assignments

*Please review the academic integrity agreement below before completing any assignments to ensure they are completed in accordance with this policy and the requirements of each assessment outlined below.

Chapter Practice Evaluations

Each unit has chapter evaluations. These are in the form of an 8-question multiple-choice quiz. These quizzes are timed, non-proctored and are closed book and closed notes. You will have 15 minutes to complete each quiz. The quizzes will be taken online through the Brightspace course site. These quizzes do not contribute to your final overall grade, but they must be completed. The questions for these assessments are pulled from a pool of questions used for the formative Unit exams.  Doing well on the quizzes will help prepare you for the formative Unit exams. You can only take each quiz once, and these assessments can be reviewed through Class Progress after completion.

Unit Exams

There are four non-proctored exams after Units 1 – 4. These exams consist of 15-20 questions and will be taken through Brightspace. These exams consist of material restricted to a single unit and contain questions very similar to the practice evaluation quizzes. You will have up to 45 minutes to complete these exams and once started you must complete the assessment. Exams should be taken closed notes, closed books and in accordance with the academic integrity agreement. You can only take these once and these can be reviewed through Class Progress after completion.

Discussion Board Posts

There are three required discussion board posts. Please see Brightspace for a full description of the assignment. This assessment is designed to help with critical thinking skills and to identify any key misconceptions you may have over the material.

Final Project

The biochemistry course will cover chapters 1 – 9, 11, 13, 14, 16 – 20, 22, 23, 25, and 26 in Harper’s Illustrated Biochemistry textbook. For the final project, you will choose one of the remaining chapters to create a video presentation. For this presentation, you will become the teacher and present the chapter to your classmates in a video format presentation. You will then upload your video to YouTube.

It will be a 4 step Final Project.  

  • Step 1 – due in Unit 1 is the chapter selection submission.
  • Step 2 – due in Unit 2 is the outline submission.
  • Step 3 – due in Unit 3 is the rough draft presentation submission.
  • Step 4 – due in Unit 4 is the 10-minute video presentation submission.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

CategoryPoints
Practice Evaluation Quizzes (14 required 8-question practice quizzes) 0
Unit 1 Exam 12.5
Unit 2 Exam 12.5
Unit 3 Exam 12.5
Unit 4 Exam 12.5
Discussions: 3 x 10 points 30
Final Project Unit 1: Chapter 0.5
Final Project Unit 2: Outline 0.5
Final Project Unit 3: Visuals 1
Final Project Unit 4: Video 18
Total100

Grade Scale

Grade Points Grade Point Average (GPA)
A 94 – 100% 4.00
A- 90 – 93% 3.75
B+ 87 – 89% 3.50
B 84 – 86% 3.00
B- 80 – 83% 2.75
C+ 77 – 79% 2.50
C 74 – 76% 2.00
C- 70 – 73% 1.75
D 64 – 69% 1.00
F 00 – 63% 0.00

Schedule

Unit 1: Mon May 19 – Mon May 26

Unit 2: Tue May 27 – Fri June 6

Unit 3: Sat June 7- Mon 16

Unit 4: Tue June 17 – Fri June 27

UNIT  TOPICS

READINGS

ASSESSMENTS 

Unit 1

Biochemistry & Water

Amino Acids & Primary Structure Determination  

Proteins: Higher Orders of Structure

 

 

Harper’s Illustrated Biochemistry, 31st Ed.

  • Chapter 1
  • Chapter 2
  • Chapter 3
  • Chapter 4
  • Chapter 5 – SECTION: Four Orders of Protein Structure Secondary Structure

Chapter Practice Evaluations

Discussion: Introduction and Video Practice

Final Project Assignment for Unit 1

Unit 1 Exam

Unit 2

Basics of Enzymes and Clinical Uses

Enzyme Kinetics & Regulation

Free Energy & the Electron Transport Chain

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 6 – SECTION: The Allosteric Properties of Hemoglobins Result from their Quaternary Structures
  • Chapter 7
  • Chapter 8
  • Chapter 9
  • Chapter 11
  • Chapter 13

Chapter Practice Evaluations

Discussion: Venn Diagram

Final Project Assignment for Unit 2

Unit 2 Exam

Unit 3

Overview of Metabolism and Hormone Signaling

Glycolysis and the TCA

Glycolysis and the TCA

Pentose Phosphate Pathway, Galactose & Fructose Metabolism

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 14
  • Chapter 42
  • Chapter 16
  • Chapter 17
  • Chapter 18
  • Chapter 19
  • Chapter 20

Chapter Practice Evaluations

Discussion: Crossword Puzzle

Final Project Assignment for Unit 3

Unit 3 Exam 

Unit 4 

β-Oxidation and Ketogenesis

Fatty Acid Synthesis

Lipoprotein Metabolism

Cholesterol Synthesis & Regulation

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 22
  • Chapter 25 – SECTION: Adipose Tissue is the Main Store of Triacylglycerol in the Body
  • Chapter 23
  • Chapter 25
  • Chapter 26

Chapter Practice Evaluations

Final Project Submission

Unit 4 Exam

Student Resources

Accommodations

Any student who would like to request, or ask any questions regarding, academic adjustments or accommodations must contact the Student Access Center at (207) 221-4438 or pcstudentaccess@une.edu. Student Access Center staff will evaluate the student's documentation and determine eligibility of accommodation(s) through the Student Access Center registration procedure.

Online Peer Support

Togetherall is a 24/7 communication and emotional support platform monitored by trained clinicians. It’s a safe place online to get things off your chest, have conversations, express yourself creatively, and learn how to manage your mental health. If sharing isn’t your thing, Togetherall has other tools and courses to help you look after yourself with plenty of resources to explore. Whether you’re struggling to cope, feeling low, or just need a place to talk, Togetherall can help you explore your feelings in a safe supportive environment. You can join Togetherall using your UNE email address.

Information Technology Services (ITS)

Students should notify their Student Support Specialist and instructor in the event of a problem relating to a course. This notification should occur promptly and proactively to support timely resolution.

ITS Contact: Toll-Free Help Desk 24 hours/7 days per week at 1-877-518-4673.

Career Ready Program

The College of Professional Studies supports its online students and alumni in their career journey!

The Career Ready Program provides tools and resources to help students explore and hone in on their career goals, search for jobs, create and improve professional documents, build professional network, learn interview skills, grow as a professional, and more. Come back often, at any time, as you move through your journey from career readiness as a student to career growth, satisfaction, and success as alumni.

Online Student Support

Your Student Support Specialist is a resource for you. Please don't hesitate to contact them for assistance, including, but not limited to course planning, current problems or issues in a course, technology concerns, or personal emergencies. Questions? Email: prehealth@une.edu.

Online Peer Support

Togetherall is a 24/7 communication and emotional support platform monitored by trained clinicians. It’s a safe place online to get things off your chest, have conversations, express yourself creatively, and learn how to manage your mental health. If sharing isn’t your thing, Togetherall has other tools and courses to help you look after yourself with plenty of resources to explore. Whether you’re struggling to cope, feeling low, or just need a place to talk, Togetherall can help you explore your feelings in a safe supportive environment. You can join Togetherall using your UNE email address.

Instructor and Support Contact Information

Check Brightspace for specific instructor and support specialist contact information.

UNE Libraries

Further Assistance

Your student service advisor monitors course progression and provides assistance or guidance when needed. They can assist questions regarding ordering course materials, University policies, billing, navigating the course in Brightspace, and more.

Policies

Attendance Policy

Online students are required to submit a graded assignment/discussion prior to Sunday evening at 11:59 pm ET of the first week of the term. If a student does not submit a posting to the graded assignment/discussion prior to Sunday evening at 11:59 pm ET, the student will be automatically dropped from the course for non-participation. Review the full attendance policy.

Assignments

Late assignments will be accepted up to 3 days late; however, there is a 10% grade reduction (from the total points) for the late submission. After three days the assignment will not be accepted. Discussion posts: If the initial post is submitted late, but still within the discussion board week, there will be a 10% grade reduction from the total discussion grade (e.g., a 3 point discussion will be reduced by 0.3 points). Any posts submitted after the end of the Discussion Board week will not be graded. Please make every effort ahead of time to contact your instructor if you are not able to meet an assignment deadline. Arrangements for extenuating circumstances may be considered by faculty.

Proctored Examinations

Your course may have proctored exams. Please see your course for full details, access, testing requirements, and guidelines.

Students must follow all proctoring requirements for their exams to be credited. Please contact your instructor for specific feedback.

Exam Attempts Policy

Students will receive two attempts at all proctored examinations. The higher score of the two attempts will be calculated into the final grade.

All students are encouraged to use a second attempt on their exams in order to improve their overall performance in the course.

Information about exam attempts can be found in your course.

Technology Requirements

Please review the technical requirements for UNE Online Programs: Technical Requirements

Course Length

A schedule of lectures and assignments is included in this syllabus.

Courses in the program are equivalent to one-semester courses designed to be completed in 6 or 8 weeks.

  1. Enrollment in the course begins the day your section opens which is listed in the Academic Calendar found on the Student Success Portal.
  2. Course due dates, start and end dates are in respect to Eastern Time.

Withdrawal and Refund Policies

Please review the policies in your confirmation email. Contact PreHealth@une.edu with any questions.

Grade Policy

Students are expected to attempt and complete all graded assignments and proctored exams by the end date of the course. Contact support with any questions.

Transcripts

Due to the Family Educational Rights and Privacy Act, only the student may request official transcripts. This may be done online by going to the University of New England Registrar website and following the directions on the page.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable.

Academic dishonesty includes, but is not limited to the following:

  1. Cheating, copying, or the offering or receiving of unauthorized assistance or information.
  2. Fabrication or falsification of data, results, or sources for papers or reports.
  3. Action which destroys or alters the work of another student.
  4. Multiple submission of the same paper or report for assignments in more than one course without permission of each instructor.
  5. Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.

Attendance Policy

8 week: Students taking online graduate courses through the College of Professional Studies will be administratively dropped for non-participation if a graded assignment/discussion post is not submitted before Sunday at 11:59 pm ET of the first week of the term. Reinstatement is at the purview of the Dean's Office.

16 week: Students taking online graduate courses through the College of Professional Studies will be administratively dropped for non-participation if a graded assignment/discussion post is not submitted before Friday at 11:59 pm ET of the second week of the term. Reinstatement is at the purview of the Dean's Office.

Student Handbook Online - Policies and Procedures

The policies contained within this document apply to all students in the College of Professional Studies. It is each student's responsibility to know the contents of this handbook.

UNE Online Student Handbook

UNE Course Withdrawal

Please contact your student support specialist if you are considering dropping or withdrawing from a course. The last day to drop for 100% tuition refund is the 2nd day of the course. Financial Aid charges may still apply. Students using Financial Aid should contact the Financial Aid Office prior to withdrawing from a course.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable. For information about plagiarism and academic misconduct, please visit UNE Plagiarism Policies.

Academic dishonesty includes, but is not limited to the following:

  1. Cheating, copying, or the offering or receiving of unauthorized assistance or information.
  2. Fabrication or falsification of data, results, or sources for papers or reports.
  3. Action which destroys or alters the work of another student.
  4. Multiple submissions of the same paper or report for assignments in more than one course without permission of each instructor.
  5. Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.