Science Prerequisites for Health Professionals

CHEM 1021: Organic Chemistry II

Credits - 3


Online Organic Chemistry II:  This course is designed to give the student, interested in the health professions, the depth of a second semester of organic chemistry exploring reactivity and synthesis. The goals of this course are to provide students with the logic and foundation to organic chemistry topics that will be needed in his/her professional studies. Students will be introduced to a wide range of organic chemistry reactions. Students will learn to predict reaction outcomes and build an understanding of how molecules are synthesized. These are topics that are needed for entrance exams in the health professions.

The course is designed to take lecture and lab concurrently for four credits. However, students have the option to take the lecture only (three credits) or lab only (one credit).  

Course Prerequisite:: One semester of college level organic chemistry with lab.



All assigned readings are available freely online. 


  1. Required: Subscription to Achieve ($42). Enrollment details are available in Brightspace.
  2. Strongly Recommended:  An organic chemistry model kit such as this kit on Amazon.


Mandatory UNE-approved webcam and whiteboard – To be used during proctored exams


Learning Objectives and Outcomes

Program Outcomes

In lecture courses, students should be able to:

  1. Communicate scientific concepts and information clearly.
  2. Illustrate fundamental laws, theories, and principles of scientific disciplines.
  3. Apply knowledge and critical thinking skills to scientific problems.

In lab courses, students should be able to:

  1. Ask a question or define a problem that can be tested.
  2. Hypothesize possible result(s).
  3. Plan and/or conduct an investigation individually and/or collaboratively to produce data to serve as the basis for evidence.
  4. Analyze data using tools, technologies, and/or models (i.e. computational, mathematical, graphical, etc.) in order to make valid and reliable scientific claims or determine an optimal design solution.
  5. Communicate the results by constructing an explanation based on multiple pieces of valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future.
  6. Apply scientific ideas, principles, and/or evidence gained from various experiments, as well as other observations and/or research, to provide an explanation of phenomena and solve design problems, taking into account possible unanticipated effects.

Course Objectives

  1. Rationalize the outcomes for reactions that precede via enolate intermediates generated from carbonyl-containing compounds.
  2. Explore the reactivity of different chemical reagents with α,β-unsaturated ketones. 
  3. Predict the reactivity of alkyl halides (substitution and elimination). 
  4. Explain the applications of nucleophilic substitution and elimination reactions (oxidations, alpha alkylations).
  5. Describe the electrophilic addition reactions of alkenes and alkynes.
  6. Predict the properties and reactivity of conjugated, aromatic, anti-aromatic, or non-aromatic molecules.
  7. Explore the reactions of aromatic compounds and understand what governs regioselectivity depending on the substitution pattern of the aromatic compound. 
  8. Predict products for simple pericyclic reactions.
  9. Explain the mechanisms of radical reactions.
  10. Develop short syntheses of target molecules.


On the course start date, students will have access to orientation. This must be completed to be able to gain access to the first module in the course. Students must complete the first module to gain access to the next one. We recommend that students spend about 15 hours per week to complete a course in 16 weeks. When trying to complete the course in less than 16 weeks, we typically see students do this successfully within 12-14 weeks. Instructors will be timely in grading and feedback, but it will not be instant.



Each week, you will explore the new topics through the readings, videos, and worksheets. The worksheets are a place for you to take notes, draw, and try to answer problems. The materials are designed to help you walk through key ideas for the week. You can read the texts or watch the videos or play a game while you are doing the worksheets. You might find it effective to move back and forth between these activities. In fact, some of the videos will work through examples in the worksheets! Research shows that active engagement can increase your understanding and retention of the materials. To that end, you are strongly encouraged to print each week’s guided worksheets out first to have them on-hand while reading or viewing the learning materials. As they are a form of practice and engagement, you will receive points for completion alone.  If you are not understanding a topic through these materials, please contact the instructor!

Sapling Homework 

Each week, you will complete one or two short homework assignments in the Sapling system.  These homework assignments will be a chance for you to assess your understanding of the key concepts covered during that week.

In these activities, you can view hints without being penalized. You are also able to attempt each question multiple times, but be aware that you will receive a small penalty (5%) for each attempt after your first.  Note that you can compare your attempts to chart your progress with a question and review your work. Finally, be sure to review the feedback that you receive to better understand the correct responses.  You will be able to see the correct answer after you have submitted your assignment.

Sapling Quizzes

You will complete four shorter quizzes in the Sapling platform. These quizzes will be approximately 10-15 questions and you will have approximately 25 minutes to complete them. Each quiz will be worth 25 points. They will usually cover 2-3 weeks of material and will ensure that you are retaining the material as we progress through the semester.

Discussion Boards

There will be four discussion boards this semester. There is an introductory board to foster a sense of community. There will be two discussion boards on topics of metacognition (how to study and learn). The last discussion board will involve a project on the impact that organic synthesis has had on society.


There are six activities in this course (and one optional extra credit activity!). These activities will ask you to apply the knowledge that you are learning. One assignment will involve you recording a description of a reaction mechanism. The “roadmaps” will ask you to help provide reagents for the synthesis of a target molecule. The synthesis projects are an opportunity to design your own roadmap to a target molecule. There is also one assignment in which you will summarize the content from the previous class into a table.  

Midterm Exams

You will complete two mid-term exams in the Sapling platform. These quizzes will be worth 50 points each. The exams will be approximately 25 questions and you will have about 40 minutes to complete them. They will usually cover 3-5 weeks of material and will ensure that you are retaining the material as we progress through the semester. 

Final Exam

This will be a cumulative exam.  It will be a timed and proctored exam. There will be approximately 50 questions.  You will have 90 minutes to complete the exam and you may use the official UNE whiteboard. This assignment is worth 100 points toward your final grade.

This exam must be taken through ProctorU. See UNE’s Online ProctorU Site for information about signing up and scheduling your exam. The official UNE webcam is required (see the Course Materials section, above, for more information).

For proctored finals, grades will be posted 48-72 hours after taking the exams. At that time, you can expect an unofficial transcript.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

Assignment CategoryNumber of Assignments & PointsTotal Point Values
Sapling Homework12 x 10 pts, 5 x 5 pts145 points
Sapling Quizzes 4 x 20 pts80 points
Worksheets13 x 5 pts65 points
Discussions Boards4 x 10 pts40 points
ActivitiesRoadmap 1 (10 pts) Roadmap 2 (20 pts) Summary (5 pts) Mechanism (20 pts) Synthesis 1 (20 pts) Synthesis 2 (10 pts)85 points
Midterm Exams2 x 50 pts100 points
Final Exam1 x 100 pts100 points
Total615 points

Grade Scale

Grade Points Grade Point Average (GPA)
A 94 – 100% 4.00
A- 90 – 93% 3.75
B+ 87 – 89% 3.50
B 84 – 86% 3.00
B- 80 – 83% 2.75
C+ 77 – 79% 2.50
C 74 – 76% 2.00
C- 70 – 73% 1.75
D 64 – 69% 1.00
F 00 – 63% 0.00







Week 0: Prior Knowledge for Organic Chemistry II

How to Use Achieve HW


Introduction to Organic Chemistry II


Achieve HW


More Review of Organic Chemistry I

Achieve HW


Introduction to Enolate Reactions

Achieve HW


Conjugate Addition Reactions

Achieve Homework


Review and Apply

Roadmap Activity
Midterm #1


Nucleophilic Substitution and Elimination Reactions

Achieve Homework


Predicting the Predominant Pathway in Substitution and Elimination Reactions

Summary Activity
Achieve Homework


Reactions of Alcohols, Amines, and Ethers

Mechanism Activity

Achieve HW

Synthesis Proposal #1


Alpha Alkylations

Synthesis Activity
Achieve Homework


Review and Apply

Roadmap Activity
Midterm #2


Electrophilic Additions to Alkenes and Alkynes

Achieve HW


Concerted Electrophilic Additions

Achieve HW


Conjugation, Aromaticity, and Pericyclic Reactions

Achieve HW


Electrophilic Aromatic Substitutions

Synthesis Activity


Radicals and Radical Polymerizations

Achieve HW
Discussion Continued


Review and Apply (Final Exam)

Extra Credit Roadmap
Final Exam

Student Resources

Student Portal: Your Best UNE Resource

We created the UNE Online Student Portal, specifically for you, to be a useful collection of information to support you as you navigate your online course(s).

From the UNE Online Student Portal, you can access:

  • Blackboard/Brightspace
  • Technical Support
  • Library
  • Bookstore
  • UNE Email
  • U-Online

The portal also features:

  • Dates to Remember
  • Support and Services
  • Contact information for your Support Specialist
  • Academic Resources - links to the Academic Calendar, Registrar and Academic Calendar
  • Financial - links to eBilling, Financial Aid and Student Accounts

Instructor and Support Contact Information

Check Blackboard/Brightspace for specific instructor and support specialist contact information.

Further Assistance

Your student service advisor monitors course progression and provides assistance or guidance when needed. They can assist questions regarding ordering course materials, University policies, billing, navigating the course in Blackboard/Brightspace, and more.

Student Lounge

The Student Lounge Discussion Board is a designated support forum in which students may engage with each other and grapple with course content. Feel free to post questions, seek clarification, and support each other, but be mindful of UNE's Academic Integrity Policy.

Your instructor will monitor this forum. However, if you are seeking specific and timely answers to questions about course content or your personal grades, please contact your instructor via course messages. For questions about course materials, program policy, and how to navigate and proceed through the course, please contact your Student Service Advisor through the Student Portal.


Proctored Examinations

The University of New England has contracted with ProctorU to provide students with the most convenient online exam proctoring system. This system provides a simple, no cost to the student, secure, online proctor for exams and allows the student to take all the exams at home and on their own schedule.

Upon enrollment into the course, each student will register with ProctorU and establish a login name and password. This will give the student access to all of ProctorU's services. When ready, students will schedule each of their proctored exams with ProctorU. Exams must be scheduled at least 72 hours in advance to avoid fees. Prior to taking their exams, students must be sure that they have downloaded the ProctorU Chrome or Firefox extension and are using the most current version of Chrome or Firefox. They must also be sure their testing site's connection meets the minimum requirements by using ProctorU's "Test It Out" utility.

Upon the exam day and hour, students will log in to ProctorU and click on "exams". After following the procedures outlined at ProctorU's web site, the student will log in to Blackboard/Brightspace and locate their correct exam. The proctor will then allow student access to that exam.

Students must use ProctorU and must follow all proctoring requirements for their exams to be credited.

Proctored exams are not available for review at any time. You will not be able to see the questions, nor the answers you've given, after completing the exams. Please contact your instructor for specific feedback.

Course Discussions

Discussion board assignments cover interesting current events or materials related to this course that contribute to a deeper understanding of key concepts and allow you to interact with your classmates and the instructor. Each assignment may require you to conduct internet research, read additional materials (a short journal or magazine article), visit a specific webpage, AND/OR view a short video prior to writing a response following the specific guidelines in the assignment.

To earn full credit: you will need to post a response to the discussion topic, respond to the original posts of at least two other students, and then contribute meaningfully to an ongoing discussion. You will need to post your initial response before you will see any posts from your classmates. Please keep in mind that only this initial response is included in your assignment grade, so make sure you have followed all of the guidelines and written a complete response prior to submitting the post. For special cases where one or two students are accelerating faster through the course, the instructor will participate in the discussion so that everyone has the opportunity to interact.

Please see Blackboard/Brightspace for a full description, along with specific guidelines, for each assignment. Discussion board assignments should be completed, along with all other assignments in the course, in the order that they appear. Due to the course design, you may be unable to take a proctored exam if you do not complete all assignments that appear prior to that exam.

Please also refer to the Grading Policy/Grade Breakdown section of the syllabus to learn the percentage of your grade that each discussion board assignment is worth.

Technology Requirements

Please review the technical requirements for UNE Online Graduate Programs:

Course Length

A schedule of lectures and assignments is included in this syllabus. This is, however a self-paced course and you can complete the course in less time.

  1. Courses in the SPHP program are equivalent to one-semester courses designed to be completed in 16 weeks
  2. Enrollment in the course begins the day your section opens which is listed in the Academic Calendar found on the Student Success Portal.
  3. Course start and end dates are in respect to Eastern Time.

Withdrawal and Refund Policies

Please visit this page to review the withdrawal and refund policies.

Grade Policy

Students are expected to attempt and complete all graded assignments and proctored exams by the end date of the course. To view the incomplete grade policy, please click here.


Due to the Family Educational Rights and Privacy Act, only the student may request official transcripts. This may be done online by going to the University of New England Registrar website and following the directions on the page.

To view your unofficial UNE student transcript:

  1. Log into uonline at
  2. Select Student Services
  3. Select Student Records
  4. Select Academic Transcript

To request your official UNE student transcript:

Please review your Unofficial Transcript prior to requesting an Official Transcript.

  1. Log into uonline at
  2. Select Student Services
  3. Select Student Records
  4. Select Request Printed/Official Transcript
  5. Follow the prompts

After you click Submit Request, your official transcript will be put into the queue to be printed in the Registrar’s Office.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable.

Academic dishonesty includes, but is not limited to the following:

  1. Cheating, copying, or the offering or receiving of unauthorized assistance or information.
  2. Fabrication or falsification of data, results, or sources for papers or reports.
  3. Action which destroys or alters the work of another student.
  4. Multiple submission of the same paper or report for assignments in more than one course without permission of each instructor.
  5. Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.