Syllabus

Post Baccalaureate in Pre-Health

CHEM 1031: Organic Chemistry II Lecture and Lab – 12 weeks

Credits - 4

Description

This course is designed to give the student, interested in the health professions, the depth of a second semester of organic chemistry exploring reactivity and synthesis. The goals of this course are to provide students with the logic and foundation to organic chemistry topics that will be needed in his/her professional studies. Students will be introduced to a wide range of organic chemistry reactions. Students will learn to predict reaction outcomes and build an understanding of how molecules are synthesized. The course also incorporates a laboratory experience that places an emphasis on understanding the concept of the labs and the scientific method, since today’s healthcare professionals are expected to have a general understanding of how science and the scientific method contribute to their profession.

The course and labs will introduce the student to important laboratory techniques covered on most professional entrance exams. 

Course Prerequisite: One semester of college level organic chemistry with lab.

Materials

Learning Objectives and Outcomes

Course Objectives

Lecture

1. Rationalize the outcomes for reactions that precede via enolate intermediates generated from carbonyl-containing compounds.
2. Explore the reactivity of different chemical reagents with α,β-unsaturated ketones. 
3. Predict the reactivity of alkyl halides (substitution and elimination). 
4. Explain the applications of nucleophilic substitution and elimination reactions (oxidations, alpha alkylations).
5. Describe the electrophilic addition reactions of alkenes and alkynes.
6. Predict the properties and reactivity of conjugated, aromatic, anti-aromatic, or non-aromatic molecules.
7. Explore the reactions of aromatic compounds and understand what governs regioselectivity depending on the substitution pattern of the aromatic compound. 
8. Predict products for simple pericyclic reactions.
9. Explain the mechanisms of radical reactions.
10. Develop short syntheses of target molecules.

Lab

1. Explain lab safety protocols.
2. Demonstrate the necessary glassware set-up to run a reaction. 
3. Demonstrate the theory & practice of reflux.
4. Describe how to separate a compound from solvent. 
5. Calculate theoretical yield and percent yield.
6. Analyze a reaction outcome using melting point determination and spectral techniques.
7. Explain a model of how a compound responds to energy or light. 
8. Explore the reactivity of organic compounds

Assignments

Worksheets

Each week, you will explore the new topics through the readings, videos, and worksheets. The worksheets are a place for you to take notes, draw, and try to answer problems. The materials are designed to help you walk through key ideas for the week. You can read the texts or watch the videos or play a game while you are doing the worksheets. You might find it effective to move back and forth between these activities. In fact, some of the videos will work through examples in the worksheets! Research shows that active engagement can increase your understanding and retention of the materials. To that end, you are strongly encouraged to print each week’s guided worksheets out first to have them on hand while reading or viewing the learning materials. As they are a form of practice and engagement, you will receive points for completion alone.  If you are not understanding a topic through these materials, please contact the instructor!

Achieve Homework 

Each week, you will complete one or two short homework assignments in the Achieve system.  These homework assignments will be a chance for you to assess your understanding of the key concepts covered during that week.

In these activities, you can view hints without being penalized. You are also able to attempt each question multiple times, but be aware that you will receive a small penalty (5%) for each attempt after your first. Note that you can compare your attempts to chart your progress with a question and review your work. Finally, be sure to review the feedback that you receive to better understand the correct responses.  You will be able to see the correct answer after you have submitted your assignment.

Achieve Quizzes

You will complete weekly quizzes in the Achieve platform. Each quiz will be worth 25 points and you will have an hour for each quiz. They will ensure that you are retaining the material as we progress through the semester.

Discussion Boards

There will be four discussion boards this semester. There is an introductory board to foster a sense of community. There will be two discussion boards on topics of metacognition (how to study and learn). The last discussion board will involve a project on the impact that organic synthesis has had on society.

Activities

These activities will ask you to apply the knowledge that you are learning.

Prelab Quizzes

Each week, you will complete the prelab quizzes to help understand the key foundational information that will be needed to complete the laboratory experiment. 

Laboratory Report  

Each week, you will complete one or two laboratory reports. You will analyze the data, formulate answers about the results of the experiment, and answer critical thinking questions.

Final Exam

This will be a cumulative exam.  It will be a timed and proctored exam. There will be approximately 60 questions.  You will have 120 minutes to complete the exam, and you will be allowed to use the official UNE whiteboard. You may also view this Periodic Table in an open browser tab (no printed copies allowed) as well as these NMR Tables and this IR Table.

This assignment is worth 100 points toward your final grade. Two attempts will be available for this exam. 

This exam must be taken through ProctorU. See UNE’s Online ProctorU Site for information about signing up and scheduling your exam. The official UNE webcam is required (see the Course Materials section, above, for more information).

For proctored finals, grades will be posted 48-72 hours after taking the exams. At that time, you can expect an unofficial transcript.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

Assignment Category	Number of Assignments & Points	Total Point Values	Percent
Achieve Homework	7 x 20; Intro 5	145	16.86%
Achieve Quizzes	7 x 25 pts	175	20.35%
Worksheets	7 x 5 pts	35	4.07%
Discussions Boards	4 x 10 pts	40	4.65%
Activities	Synthesis HW1 and 2; Roadmap 1 and 2 (10 ea), Summary Sub/Elim (5)	45	5.23%
Prelab Quizzes	10 x 5 pts	50	5.81%
Lab Reports	10 x 25 pts	250	29.07%
Final Exam/Lab Final	1 x 120 pts	120	13.95%
	Total	860	100.00%

Grade Scale

Grade	Points Grade	Point Average (GPA)
A	94 – 100%	4.00
A-	90 – 93%	3.75
B+	87 – 89%	3.50
B	84 – 86%	3.00
B-	80 – 83%	2.75
C+	77 – 79%	2.50
C	74 – 76%	2.00
C-	70 – 73%	1.75
D	64 – 69%	1.00
F	00 – 63%	0.00