Syllabus

Master of Science in Applied Nutrition

APN 615 Nutrition and Metabolism – Fall B 2018

Credits - 3

Description

The metabolism of carbohydrates, protein, fats, vitamins, minerals, and water and the biological and physiological actions of these nutrients are examined. Topics include macronutrient and micronutrient absorption, transport, and excretion, the regulation of biochemical and enzymatic pathways, variability in the bioavailability of vitamins and minerals, and the impacts of nutrient toxicity and deficiency in humans and animal models.

Materials

Gropper, S. A. S., Smith, J. L., & Carr, T. P. Advanced nutrition and human metabolism; 2018.

Learning Objectives and Outcomes

Program Objectives

This course will help you satisfy the following program objectives:

Develop and utilize nutrition concepts and best-practices for nutrition and health promotion initiatives

Apply core research principles to measure the nutrition status and environment of individuals and communities

Interpret and modify explanations of complex nutrition concepts for various audiences

Research, develop and disseminate evidence-based and theory driven educational materials and work-products at an audience appropriate level for topics related to nutrition and health promotion

Course Objectives

In this course you will:

Evaluate the role of macro and micro nutrients in health and disease
Distinguish the complex interaction of cell biology, biochemistry, and physiology in the study of nutrition
Analyze current articles/reviews in the field of nutritional science as they relate to the topics of the course

Course Outcomes

In this course you will:

Summarize the processes of digestion, absorption, metabolism, excretion and biochemical function of macronutrients, and vitamins, and minerals
Summarize the regulation of lipid, carbohydrate, and protein digestion, absorption, transport, tissue and cellular metabolism
Examine the scientific basis for establishing micro and macronutrient requirements and how to apply to various populations and age groups
Examine metabolic pathways dependent on specific nutrients with an emphasis on how vitamins and/or mineral facilitate specific biochemical functions
Discuss the basis of how nutrient deficiencies and excesses result in metabolic abnormalities with functional and potentially toxic consequences
Evaluate deficiency and toxicity signs and symptoms associated with each nutrient
Distinguish how macronutrient and micronutrient metabolism affect disease etiology and their roles in disease prevention
Analyze physiological, biochemical and metabolic changes associated with micro and macro nutrient intake as it relates to select metabolic diseases
Compare and contrast relevant scientific literature and synthesize existing knowledge in nutrition and metabolism with new research information.

Assignments

The IRB Proposal: You will complete a 15-20 page IRB proposal based on a hypothetical study of a nutrient.

The Presentation: You will deliver a 10-15 minute professional presentation based on the information in your proposal.

Nutrient Introduction: You will share the preliminary information necessary to compose your IRB proposal.

Literature Review: You will complete a 5-10 page literature review of your topic.

Data Analysis: You will submit the data analysis portion of your IRB proposal as an assignment.

Instructor Feedback: After submitting your Methods/Data Analysis section, you will schedule a meeting with your instructor to discuss your IRB proposal.

Case Studies: You will complete four case study assignments focusing on different nutritional scenarios/questions.

Krebs Cycle and Nutrient Multimedia Projects: You will complete a creative, multimedia depiction of the Krebs Cycle, as well as one of your IRB proposal nutrient.

Nutrient Deficiency Assignment: You will analyze skeletal evidence and share your opinion on the cause of observed disease as a result of nutritional deficiency.

Diet Comparison Assignment: You will submit a report examining the nutritional attributes and scientific validity of five established dietary practices.

Unit Quizzes: You will complete weekly quizzes designed to check your understanding of key concepts from the weekly readings in the textbook.

Discussion Board: You will be required to participate in discussions. Initial posts are due on Sunday 11:59 p.m., and responses are due by Tuesday, 11:59 p.m. If the initial post and response are not submitted within the discussion week you will be given a zero. Posts submitted after the discussion week will not be graded.

Your success in the course relies on robust discussion, critical thinking, and peer-response. Weekly posts responding to prompts posed are meant to facilitate a deeper understanding of the broader themes of the course as well as enrich the readings, handouts, and lectures. Your initial response should be no less than 400 words. Peer-responses should be no less than 200 words and must be thoughtful, contain compliment as well as constructive criticism, and maintain a professional tone.

Furthermore, in regard to all assignments, please observe the following:

All assignments must be completed using AMA formatting where appropriate.
All times refer to Eastern Time (ET).
All questions about assignments, and all questions in general, should be sent through email.

Writing Statement

As professionals in the field, you will consistently be expected to clearly and concisely articulate advanced concepts for diverse audiences at a variety of educational levels.

Graduate students are expected to produce their best quality work, including screening their work prior to submission for clarity, grammatical, spelling, formatting and mechanical issues.

While there is often a portion of each assignment’s rubric dedicated specifically to grammar, spelling, mechanics, and formatting, it is critical to understand that failure to submit work that has been adequately proofed may result in a reduction of points in other areas of the rubric. These may include, but are not limited to metrics rating professionalism or content knowledge and synthesis; work submitted in graduate courses should provide evidence of strategic reading, writing, and academic speaking skills essential for success in the discipline.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

IRB Proposal	15
Presentation	7
Nutrient Submission	2.5
Nutrient Introduction	2.5
Literature Review	4
Data Analysis/Methods Section	4
Case Studies - 4 @ 2 pts. each	8
Krebs Cycle Multimedia Project	2.5
Nutrient Multimedia Project	2.5
Nutrient Deficiency Assignment	5
Diet Comparison Assignment	5
ePortfolio Reflection	5
Unit Quizzes - 7 @ 2 pts. each	14
Discussion Board (excluding Case Studies) - 9 @ 2 pts. each, 2 @ 1 pt	20
Instructor Feedback	2
Student Syllabus Contract	1
Total	100

Schedule

Weekly Dates

Week One: 10/24 – 10/30

Week Two: 10/31 – 11/6

Week Three: 11/7 – 11/13

Week Four: 11/14 – 11/20

Week Five: 11/21 – 11/27

Week Six: 11/28 – 12/4

Week Seven: 12/5 – 12/11

Week Eight: 12/12 – 12/16

Major Due Dates

Discussion Board Prompts	Every Sunday and Tuesday
Case Studies	Same as Discussion Board; please see individual prompts for additional details
Nutrient Submission	Tuesday, 10/30
Nutrient Introduction	Tuesday, 11/06
Krebs Cycle & Nutrient Multimedia Project	Sunday, 11/11
Nutrient Deficiency Assignment	Tuesday, 11/13
Diet Comparison Assignment	Sunday, 11/25
Literature Review	Tuesday, 11/27
Data Analysis/Methods Section	Tuesday, 12/04
Presentation	Sunday, 12/09
IRB Proposal	Tuesday, 12/11
Nutrient Multimedia Project	Sunday, 12/16
ePortfolio Reflection	Sunday, 12/16

Week One

Weekly Learning Outcomes

This week you will:

Identify the components of the cells/ organelles and discuss their functions
Discuss apoptosis
Analyze apoptotic cell death and understand the mechanisms involved
Distinguish the roles of cellular proteins including receptors and enzymes
Discuss energy transformation and heat production related to nutrient utilization
Identify the structures of the digestive system and discuss the absorptive processes
Summarize selected disorders of the digestive tract
Identify and discuss the regulatory peptides which influence and coordinate digestion and absorption

Lectures

Introduction
Lecture: The Cell and the Digestive System

Readings

Gropper and Smith Chapter 1: The Cell: A Microcosm of Life
Gropper and Smith Chapter 2: The Digestive System: Mechanism for Nourishing the Body

Additional readings listed in course.

Assignments

Submit nutrient choice and disease process for instructor approval.
Unit 1 quiz

Discussions

DB1: Introduce yourself!
DB2: Vitamin D Case Study

Initial posts due Sunday, and responses due Tuesday.

Week Two

Weekly Learning Outcomes

This week you will:

Explain the structural differences between simple and complex carbohydrates
Identify inborn errors of the TCA cycle
Discuss metabolic control of glycolysis and gluconeogenesis
Describe the dietary modifications for a gluten-free diet
Compare carbohydrate utilization in type2 and type 1 diabetes
Explain the chemistry and characteristics of fiber
Discuss the health benefits of fiber
Recommend fiber intake for different population and age groups
Compare and contrast digestion, absorption, transport, storage, and excretion of each water-soluble vitamin
Detail functions and mechanisms of action for each water-soluble vitamin
Recommend appropriate water-soluble vitamin intake for adults (based on the Recommended Dietary Allowance)
Assess the impact of water-soluble deficiencies and toxicities as they relate to health and disease

Lectures

Multiple lectures on Carbohydrates, Fiber and Water Soluble Vitamins

Readings

Gropper and Smith Chapter 3: Carbohydrates
Gropper and Smith Chapter 4: Fiber
Gropper and Smith CHapter 9: Water Soluble Vitamins

Additional readings listed in course.

Videos

The Krebs Cycle Made Simple

Assignments

Submit full introduction of nutrient (Due Tuesday)
Unit 2 quiz

Discussions

DB1: Share introductory information about the nutrient you would like to study for your IRB proposal.
DB2: GI Case Study

Initial posts due Sunday, and responses due Tuesday.

Week Three

Weekly Learning Outcomes

This week you will:

Explain the structure and biological importance of lipids
Describe the digestion, absorption, transport, and storage of lipids
Evaluate a lipid profile and make appropriate recommendations based on the lipid profile
Discuss the impact low-carbohydrate diets have on lipid metabolism
Detail the regulation of lipid metabolism
Explain the role of lipids and lipoproteins in cardiovascular disease risk
Compare and contrast digestion, absorption, transport, storage and excretion for each fat-soluble vitamin
Detail functions and mechanisms of action for each fat-soluble vitamin
Assess the impact of fat-soluble deficiencies and toxicities as they relate to health and disease

Lectures

Multiple lectures on Lipids and Fat Soluble Vitamins

Readings

Gropper and Smith Chapter 5: Lipids
Gropper and Smith Chapter 10: Fat Soluble Vitamins

Additional readings listed in course.

Assignments

Nutrient Deficiency Assignment (due Tuesday)
Krebs Cycle multimedia presentation (due Sunday)
Unit 3 quiz

Discussions

DB Post 1: Lipid Profile Case Study
DB Post 2: Please share a link to your Krebs Cycle video.

Initial posts due Sunday, and responses due Tuesday.

Week Four

Weekly Learning Outcomes

This week you will:

Describe amino acid classification
Explain how protein is digested and absorbed
Outline amino acid metabolism including transamination, deamination and disposal of ammonia, carbon skeletons/alpha-keto acids and hepatic metabolism
Discuss protein synthesis
Explain organ-specific protein metabolism
Explain protein catabolism and tissue turnover
Describe changes in body mass that occur with aging
Evaluate protein quality and amino acid needs

Lectures

Multiple lectures on Protein

Readings

Gropper and Smith Chapter 6: Protein

Additional readings listed in course.

Assignments

Begin working on Literature Review (due week 5)
Unit 4 quiz

Discussions

DB1: Please list the disordered processes related to your nutrient.
DB2: Albumin Case Study

Initial posts due Sunday, and responses due Tuesday.

Week Five

Weekly Learning Outcomes

This week you will:

Discuss the differences in energy utilization in the fed, post-absorptive, fasting and starving states
Explain the sources of energy utilized in resting muscle versus muscle during exercise
Identify the hormones involved in the regulation of metabolism during exercise
Calculate energy expenditure
Describe the difference between HiiT, Tabata, and plyometric training and the fuel sources utilized
Compare and contrast a variety of diets and dietary choices
Explain the different components of energy expenditure
Describe factors which influence energy balance and body mass

Lectures

Multiple lectures on Metabolism & Exercise, Energy Expenditure and Body Composition

Readings

Gropper and Smith Chapter 7: Integration and Regulation of Metabolism and the Impact of Exercise
Gropper and Smith Chapter 8: Energy Expenditure, Body Composition, and Healthy Weight

Additional readings listed in course.

Assignments

Diet Comparison Assignment (due Sunday)
Literature review (due Tuesday)
Unit 5 quiz

Discussions

DB1: Explain the macronutrient needs of an athlete from your favorite sport.
DB 2: Evaluate diets against national guidelines for nutritional health.

Initial posts due Sunday, and responses due Tuesday.

Week Six

Weekly Learning Outcomes

This week you will:

For each mineral: list food sources, explain digestion, absorption, and transport, discuss regulation and homeostasis, excretion and potential interactions. Describe deficiency and toxicity symptoms and assessment of nutriture.
Make appropriate recommendations using the Recommended Dietary allowance based on age/sex
Discuss body water content and distribution
Describe how water is absorbed
Assess appropriate water intake based on recommendations

Lectures

Multiple lectures on Major Minerals, Water and Electrolytes

Readings

Gropper and Smith Chapter 11: Major Minerals
Gropper and Smith Chapter 12: Water and Electrolytes

Additional readings listed in course.

Assignments

Data Analysis/Methods Section of IRB Proposal
Unit 6 quiz

Discussions

Please share your proposed method of study, research population, sample size, and which test/analysis you propose to use.

Initial posts due Sunday, and responses due Tuesday.

Week Seven

Weekly Learning Outcomes

This week you will:

For each mineral: list food sources, explain digestion, absorption, and transport, discuss regulation and homeostasis, excretion and potential interactions. Describe deficiency and toxicity symptoms and assessment of nutriture.
Make appropriate recommendations using the Recommended Dietary allowance or adequate intake based on age/sex

Lectures

Multiple lectures on Essential Trace Minerals

Readings

Gropper and Smith Chapter 13: Essential Trace Minerals

Additional readings listed in course.

Assignments

IRB proposal (due Tuesday)
Presentation (due Sunday)
Instructor Feedback (due Tuesday)
Unit 7 quiz

Discussions

DB1: Share interesting findings you discovered about your nutrient from completing the proposal.
DB2: Share the link to your IRB presentation.

Initial posts due Sunday, and responses due Tuesday.

Week Eight

Weekly Learning Outcomes

This week you will:

For each mineral: list food sources, explain digestion, absorption, and transport, discuss regulation and homeostasis, excretion and potential interactions. Describe deficiency and toxicity symptoms and assessment of nutriture. Discuss recommended intake.

Lectures

Lecture: Nonessential Trace and Ultratrace Minerals

Readings

Gropper and Smith Chapter 14: Essential Trace and Ultratrace Minerals

Additional readings listed in course.

Assignments

Course Reflection/ePortfolio Piece
Nutrient Multimedia project

Discussions

DB1: Please share your final thoughts on the class.
DB2: Please post a link to your nutrient multimedia project.

Initial posts due Sunday; responses posts optional.

Student Resources

Online Student Support

Your Student Support Specialist is a resource for you. Please don't hesitate to contact them for assistance, including, but not limited to course planning, current problems or issues in a course, technology concerns, or personal emergencies.

Questions? Visit the Student Support Applied Nutrition page

UNE Libraries:

Library Access for all students: Your library login ID and password are the same as the ones you use to log into Blackboard/Brightspace.
Applied Nutrition Database
Library Tutorial: Find an article
Library Questions: Ask a librarian or phone library staff at (207) 602-2361 or (207) 221-4330.

UNE Student Academic Success Center

The Student Academic Success Center (SASC) offers a range of services to support your academic achievement, including tutoring, writing support, test prep and studying strategies, learning style consultations, and many online resources. To make an appointment for tutoring, writing support, or a learning specialist consultation, go to une.tutortrac.com. To access our online resources, including links, guides, and video tutorials, please visit:

UNE Student Academic Success Center

Information Technology Services (ITS)

ITS Contact: Toll Free Help Desk 24 hours/7 days per week at 1-877-518-4673

Accommodations

Any student who would like to request, or ask any questions regarding, academic adjustments or accommodations must contact the Student Access Center at (207) 221-4438 or pcstudentaccess@une.edu. Student Access Center staff will evaluate the student's documentation and determine eligibility of accommodation(s) through the Student Access Center registration procedure.

Policies

AMA Writing Style Statement

In keeping with the requirements of the Journal of the Academy of Nutrition and Dietetics and the Journal of Nutrition Education and Behavior, the American Medical Association (AMA) Manual of Style, 11th edition is the required writing format for this course and is available at both UNE libraries under the title "AMA Manual." Additional support for academic writing and AMA format is provided throughout the coursework as well as at the UNE Portal for Online Students.

Online resources: AMA Style Guide

Turnitin Originality Check and Plagiarism Detection Tool

The College of Professional Studies uses Turnitin to help deter plagiarism and to foster the proper attribution of sources. Turnitin provides comparative reports for submitted assignments that reflect similarities in other written works. This can include, but is not limited to, previously submitted assignments, internet articles, research journals, and academic databases.

Make sure to cite your sources appropriately as well as use your own words in synthesizing information from published literature. Webinars and workshops, included early in your coursework, will help guide best practices in AMA citation and academic writing.

You can learn more about Turnitin in the Turnitin Student quick start guide.

Technology Requirements

Please review the technical requirements for UNE Online Graduate Programs: Technical Requirements

Course Evaluation Policy

Course surveys are one of the most important tools that University of New England uses for evaluating the quality of your education, and for providing meaningful feedback to instructors on their teaching. In order to assure that the feedback is both comprehensive and precise, we need to receive it from each student for each course. Evaluation access is distributed via UNE email at the beginning of the last week of the course.

Attendance Policy

Online students are required to submit a graded assignment/discussion prior to Sunday evening at 11:59 pm ET of the first week of the term. If a student does not submit a posting to the graded assignment/discussion prior to Sunday evening at 11:59 pm ET, the student will be automatically dropped from the course for non-participation. Review the full attendance policy.

Late Policy

Assignments: Late assignments will be accepted up to 3 days late; however, there is a 10% grade reduction (from the total points) for the late submission. After three days the assignment will not be accepted.

Discussion posts: If the initial post is submitted late, but still within the discussion board week, there will be a 10% grade reduction from the total discussion grade (e.g., a 3 point discussion will be reduced by 0.3 points). Any posts submitted after the end of the Discussion Board week will not be graded.

Please make every effort ahead of time to contact your instructor and your student support specialist if you are not able to meet an assignment deadline. Arrangements for extenuating circumstances may be considered by faculty.

Student Handbook Online - Policies and Procedures

The policies contained within this document apply to all students in the College of Graduate and Professional Studies. It is each student's responsibility to know the contents of this handbook.

UNE Online Student Handbook

UNE Course Withdrawal

Please contact your student support specialist if you are considering dropping or withdrawing from a course. The last day to drop for 100% tuition refund is the 2nd day of the course. Financial Aid charges may still apply. Students using Financial Aid should contact the Financial Aid Office prior to withdrawing from a course.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable. For information about plagiarism and academic misconduct, please visit UNE Plagiarism Policies.

Academic dishonesty includes, but is not limited to the following:

Cheating, copying, or the offering or receiving of unauthorized assistance or information.
Fabrication or falsification of data, results, or sources for papers or reports.
Action which destroys or alters the work of another student.
Multiple submissions of the same paper or report for assignments in more than one course without permission of each instructor.
Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.