Syllabus

Undergraduate Programs

CHEM 1050: Biochemistry – 15-weeks

Credits - 4

Description

This online course serves as a guided introduction to the fundamental principles of biochemistry, providing you with a comprehensive understanding of the chemical processes that occur within living organisms. You will explore the structure, function, and regulation of biological molecules, including proteins, lipids, and carbohydrates. We will cover topics including metabolic pathways, enzymology, metabolism, and the integration of biochemical processes in cellular functions.

Topics Covered:

  1. Structure and functions of proteins and enzymes.
  2. Enzymes: kinetics, mechanism, and regulation
  3. Bioenergetics
  4. Metabolism of carbohydrates and lipids

Materials

Textbook

Rodwell VW, Bender DA, Botham KM, Kennelly PJ, Weil PA. Harper’s Illustrated Biochemistry. 32nd ed. McGraw-Hill Education LLC; 2023.  (UNE Library Access)

Webcam

An external webcam is required for proctored exams. If you do not have one, you may order one here: External Webcam.

Learning Objectives and Outcomes

Upon the completion of this course the student will be able to:

  • Appreciate the scope of biochemistry and its central role in the life sciences.
  • Explain the physical properties of water.
  • Define and apply pH, pKa, pI, and K.
  • Provide examples of how each type of R group of the amino acids contributes to their chemical properties.
  • Evaluate how enzymes facilitate chemical reactions and the necessity of metabolic cofactors or vitamins in these reactions; relate how enzyme activities and concentrations may be used in clinical diagnosis.
  • Assess the different mechanisms by which hormones signal and influence metabolic pathways allowing for homeostasis within the body.
  • Describe the metabolism of carbohydrates (glucose, galactose and fructose) and their role in generating ATP for the cell.
  • Demonstrate an understanding of lipid metabolism, transport and storage in the fed and fasted conditions.
  • Relate how amino acids are used in the processes of protein synthesis, precursors for synthesis of necessary compounds and as substrates for glucose production; determine the role of the urea cycle in coordinating amino acid catabolism and nitrogen disposal.
  • Interpret the role and regulation of the metabolism of proteins, carbohydrates, and lipids in normal physiological conditions and the changes that may occur.

Assignments

*Please review the academic integrity agreement below before completing any assignments to ensure they are completed in accordance with this policy and the requirements of each assessment outlined below.

Weekly Practice Evaluations

Each week has an end-of-week practice evaluation. They are in the form of a 10-question multiple-choice quiz. The quizzes do not contribute to students’ final overall grade but they must be completed.

Weekly Quick Self-Check

Each weekly study guide has an embedded self-check at the end of the guide. These should be used as a way to help you master the weekly content and identify areas of opportunity.. Each week you will need to submit answers for at least 3 Quick Self-Check questions.

Unit Exams

There are two proctored exams after Units 2 (midterm covers Units 1 and 2) and 4 (final covers Units 3 and 4). These exams consist of 40-50 questions. They consist of material restricted to two units and contain questions very similar to the weekly practice evaluations. You will have 60 minutes to complete the exams.

Exams will be proctored using HonorLock, closed books, and in accordance with the academic integrity agreement. You can only take the exams once. They can be reviewed through the grade book after completion.

Discussions

Units 1-4 have a discussion component(s).

  • Unit 1 is a video discussion and a problem solving mystery
  • Unit 2 is a Peer review of your final project outline and AI used to prepare for your midterm exam.
  • Unit 3 is a Peer review of your final project presentations and Venn Diagram
  • Unit 4: Sharing Observations

Final Project

For the final project, you will choose one of the textbook chapters not covered in weekly materials and create a video presentation. For this presentation, you will become the teacher and present the chapter to your classmates in a video format presentation. You will then upload your video.

There will be a 4 step Final Project.  

  • Step 1 – due in Unit 1 is the topic selection submission.
  • Step 2 – due in Unit 2 is the outline submission.
  • Step 3 – due in Unit 3 is the rough draft presentation submission.
  • Step 4 – due in Unit 4 is the 10-minute video presentation submission.

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

CategoryPoints
Practice Evaluation Quizzes (weekly required 8-question practice quizzes, ungraded) 0
Weekly Quick Self-Check (15 x 0.5 points)7.5
Midterm Exam (Units 1 and 2)21
Final Exam (Units 3 and 4)24
Week 1 Discussion: Video Introduction2
Unit 1 Discussion: Biochemical Scenarios4
Unit 2 Discussion: Final Project Outline Peer Review4
Unit 2 Discussion: Using AI to Study4
Unit 3: Final Project Presentation Peer Review4
Unit 3 Discussion: Venn Diagram - Integration of Course Content4
Unit 4 Discussion: Sharing Observations4
Final Project Unit 1: Chapter 0.5
Final Project Unit 2: Outline 2
Final Project Unit 3: Rough Draft 3
Final Project Unit 4: Presentation 15
Total 100

Grade Scale

Grade Points Grade Point Average (GPA)
A 93 – 100% 4.00
A- 90 – 92.9% 3.75
B+ 87 – 89.9% 3.50
B 83 – 86.9% 3.00
B- 80 – 82.9% 2.75
C+ 77 – 79.9% 2.50
C 73 – 76.9% 2.00
C- 70 – 72.9% 1.75
D 60 – 69.9% 1.00
F 00 – 59.9% 0.00

Schedule

Course Schedule: Fall 2026

Week 1: Sep 2 – Sep 8
Week 2: Sep 9 – Sep 15
Week 3: Sep 16 – Sep 22
Week 4: Sep 23 – Sep 29
Week 5: Sep 30 – Oct 6
Week 6: Oct 7 – Oct 13
Week 7: Oct 14 – Oct 20
Week 8: Oct 21 – Oct 27
Week 9: Oct 28 – Nov 3
Week 10: Nov 4 – Nov 10
Week 11: Nov 11 – Nov 17
Week 12: Nov 18 – Nov 24
Week 13: Nov 25 – Dec 1
Week 14: Dec 2 – Dec 8
Week 15: Dec 9 – Dec 15

Below is a general overview of the Units. For more a detailed outline please follow the weekly instructions within Brightspace.

UNIT 1 (Weeks 1 – 4)

Unit 1 Assessments

    • Weekly Practice Evaluations
    • Weekly Quick Self-Check
    • Week 1 Discussion: Video Introductions
    • Unit 1 Discussion: Biochemical Scenarios
    • Unit 1 Assignment: Choose a Topic for Final Project Presentation
Weeks

Readings

Week 1:

Foundations of Biochemistry

Harper’s Illustrated Biochemistry, 31st Ed.

  • Chapter 1
  • Chapter 2

Week 2: 

Protein Building Blocks

Harper’s Illustrated Biochemistry, 31st Ed.

  • Chapter 3
  • Chapter 4

Week 3: 

The Architecture of Proteins

Harper’s Illustrated Biochemistry, 31st Ed.

  • Chapter 5 SECTIONS: Biomedical importance, Conformation versus Configuration, Four Orders of Protein Structure , Secondary Structure and Multiple factors Stabilize Tertiary and Quaternary structure
    • Note: If a section within a chapter is listed, you are only responsible for the assigned section; if no sections are listed you are responsible for the full chapter.

Week 4: 

Oxygen Transport, Enzyme Fundamentals, and Vitamin‑Derived Cofactors

Harper’s Illustrated Biochemistry, 31st Ed.

  • Chapter 6 SECTION: The Allosteric Properties of Hemoglobins Result from their Quaternary Structures
    • Note: If a section within a chapter is listed, you are only responsible for the assigned section; if no sections are listed you are responsible for the full chapter.

UNIT 2  (Weeks 5 – 7)

Unit 2 Assessments

    • Weekly Practice Evaluations
    • Weekly Quick Self-Check
    • Unit 2 Discussion: Using AI to Study
    • Unit 2 Discussion: Final Project Outline Peer Review
    • Unit 2 Assignment: Submit Final Project Outline
    • Midterm Exam

Week 5:

Metabolic Regulation and Enzyme Kinetics

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 8
  • Chapter 9

Week 6: 

Bioenergetics: From Thermodynamics to the Mitochondrial Powerhouse

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 11
  • Chapter 13

Week 7: 

Metabolism and Hormonal Control of Energy Balance

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 14
  • Chapter 42

Midterm Exam: Review textbook, learning materials, and study guides

UNIT 3 (Weeks 8 – 11)

Unit 3 Assessments

    • Weekly Practice Evaluations
    • Weekly Quick Self-Check
    • Unit 3 Discussion: Venn Diagram – Integration of Course Content
    • Unit 3 Discussion: Final Project Presentation Peer Review
    • Unit 3 Assignment: Submit Rough Draft for Final Project Presentation

Week 8:

From Glucose to the TCA Cycle: Core Pathways, Their Regulation, and Clinical Connections

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 16
  • Chapter 17

Week 9:

Glycogen Metabolism, Gluconeogenesis, and Glucose Homeostasis

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 18
  • Chapter 19

Week 10:

Alternative Carbohydrate Pathways: Pentose‑Phosphate, Fructose, and Galactose Metabolism

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 20

Week 11:

Fatty‑Acid Mobilization, Mitochondrial Oxidation, and Ketone‑Body Metabolism

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 22
  • Chapter 25 – SECTION: Adipose Tissue is the Main Store of Triacylglycerol in the Body

UNIT 4 (Weeks 12 – 15)

Unit 4 Assessments

    • Weekly Practice Evaluations
    • Weekly Quick Self-Check
    • Unit 4 Discussion: Sharing Observations
    • Unit 4 Assignment: Submit Final Project Presentation
    • Final Exam

Week 12:

Acetyl Co-A carboxylase and Fatty‑Acid Synthesis

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 23

Week 13:

Plasma Lipoproteins and the Molecular Basis of Lipid Transport

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 25

Week 14:

Cholesterol Biosynthesis, Bile Acids and Clinical Correlates

Harper’s Illustrated Biochemistry 31st edition

  • Chapter 26

Week 15:

Final Exam and Final Project

Final Exam: Review textbook, learning materials, and study guides

Student Resources

Online Student Support

Your Student Support Specialist is a resource for you. Please don't hesitate to contact them for assistance, including, but not limited to course planning, current problems or issues in a course, technology concerns, or personal emergencies. Questions? Email: prehealth@une.edu.

Online Peer Support

Togetherall is a 24/7 communication and emotional support platform monitored by trained clinicians. It’s a safe place online to get things off your chest, have conversations, express yourself creatively, and learn how to manage your mental health. If sharing isn’t your thing, Togetherall has other tools and courses to help you look after yourself with plenty of resources to explore. Whether you’re struggling to cope, feeling low, or just need a place to talk, Togetherall can help you explore your feelings in a safe supportive environment. You can join Togetherall using your UNE email address.

Instructor and Support Contact Information

Check Brightspace for specific instructor and support specialist contact information.

UNE Libraries

Further Assistance

Your student service advisor monitors course progression and provides assistance or guidance when needed. They can assist questions regarding ordering course materials, University policies, billing, navigating the course in Brightspace, and more.

Policies

Attendance Policy

6- to 8-week courses: Students taking online courses through the College of Professional Studies will be administratively dropped for non-participation if a graded assignment/discussion post is not submitted before Sunday at 11:59 pm ET of the first week of the term. Reinstatement is at the purview of the Dean's Office.

10+ -week courses: Students taking online courses through the College of Professional Studies will be administratively dropped for non-participation if a graded assignment/discussion post is not submitted before Friday at 11:59 pm ET of the second week of the term. Reinstatement is at the purview of the Dean's Office. Review the full attendance policy.

Assignments

Late assignments will be accepted up to 3 days late; however, there is a 10% grade reduction (from the total points) for the late submission. After three days the assignment will not be accepted. Discussion posts: If the initial post is submitted late, but still within the discussion board week, there will be a 10% grade reduction from the total discussion grade (e.g., a 3-point discussion will be reduced by 0.3 points). Any posts submitted after the end of the Discussion Board week will not be graded. Please make every effort ahead of time to contact your instructor if you are not able to meet an assignment deadline. Arrangements for extenuating circumstances may be considered by faculty.

Proctored Examinations

Your course may have proctored exams. Please see your course for full details, access, testing requirements, and guidelines.

Students must follow all proctoring requirements for their exams to be credited. Please contact your instructor for specific feedback on exam questions.

Exam Attempts Policy

Students will receive two attempts at all proctored examinations. The higher score of the two attempts will be calculated into the final grade.

All students are encouraged to use a second attempt on their exams in order to improve their overall performance in the course.

Information about exam attempts can be found in your course.

Technology Requirements

Please review the technical requirements for UNE Online Programs: Technical Requirements

Course Length

A schedule of lectures and assignments is included in this syllabus.

Courses in the program are equivalent to one-semester courses designed to be completed in 6 or 8 weeks.

  1. Enrollment in the course begins the day your section opens which is listed in the Academic Calendar found on the Student Success Portal.
  2. Course due dates, start and end dates are in respect to Eastern Time.

Withdrawal and Refund Policies

Please review the policies in your confirmation email. Contact PreHealth@une.edu with any questions.

Grade Policy

Students are expected to attempt and complete all graded assignments and proctored exams by the end date of the course. Contact support with any questions.

Transcripts

Due to the Family Educational Rights and Privacy Act, only the student may request official transcripts. This may be done online by going to the University of New England Registrar website and following the directions on the page.

Academic Integrity

The University of New England values academic integrity in all aspects of the educational experience. Academic dishonesty in any form undermines this standard and devalues the original contributions of others. It is the responsibility of all members of the University community to actively uphold the integrity of the academy; failure to act, for any reason, is not acceptable.

Academic dishonesty includes, but is not limited to the following:

  1. Cheating, copying, or the offering or receiving of unauthorized assistance or information.
  2. Fabrication or falsification of data, results, or sources for papers or reports.
  3. Action which destroys or alters the work of another student.
  4. Multiple submission of the same paper or report for assignments in more than one course without permission of each instructor.
  5. Plagiarism, the appropriation of records, research, materials, ideas, or the language of other persons or writers and the submission of them as one's own.

Charges of academic dishonesty will be reviewed by the Program Director. Penalties for students found responsible for violations may depend upon the seriousness and circumstances of the violation, the degree of premeditation involved, and/or the student’s previous record of violations. Appeal of a decision may be made to the Dean whose decision will be final. Student appeals will take place through the grievance process outlined in the student handbook.