Syllabus

Science Prerequisites for Health Professionals

CHEM 1021: Organic Chemistry II – Summer 2024

Credits - 3

Description

Online Organic Chemistry II:  This course is designed to give the student, interested in the health professions, the depth of a second semester of organic chemistry exploring reactivity and synthesis. The goals of this course are to provide students with the logic and foundation to organic chemistry topics that will be needed in his/her professional studies. Students will be introduced to a wide range of organic chemistry reactions. Students will learn to predict reaction outcomes and build an understanding of how molecules are synthesized. These are topics that are needed for entrance exams in the health professions.

The course is designed to take lecture and lab concurrently for four credits. However, students have the option to take the lecture only (three credits) or lab only (one credit).  

Course Prerequisite: One semester of college level organic chemistry with lab.

Materials

Learning Objectives and Outcomes

Program Outcomes

In lecture courses, students should be able to:

1. Communicate scientific concepts and information clearly.
2. Illustrate fundamental laws, theories, and principles of scientific disciplines.
3. Apply knowledge and critical thinking skills to scientific problems.

In lab courses, students should be able to:

1. Ask a question or define a problem that can be tested.
2. Hypothesize possible result(s).
3. Plan and/or conduct an investigation individually and/or collaboratively to produce data to serve as the basis for evidence.
4. Analyze data using tools, technologies, and/or models (i.e. computational, mathematical, graphical, etc.) in order to make valid and reliable scientific claims or determine an optimal design solution.
5. Communicate the results by constructing an explanation based on multiple pieces of valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future.
6. Apply scientific ideas, principles, and/or evidence gained from various experiments, as well as other observations and/or research, to provide an explanation of phenomena and solve design problems, taking into account possible unanticipated effects.

Course Objectives

1. Rationalize the outcomes for reactions that precede via enolate intermediates generated from carbonyl-containing compounds.
2. Explore the reactivity of different chemical reagents with α,β-unsaturated ketones. 
3. Predict the reactivity of alkyl halides (substitution and elimination). 
4. Explain the applications of nucleophilic substitution and elimination reactions (oxidations, alpha alkylations).
5. Describe the electrophilic addition reactions of alkenes and alkynes.
6. Predict the properties and reactivity of conjugated, aromatic, anti-aromatic, or non-aromatic molecules.
7. Explore the reactions of aromatic compounds and understand what governs regioselectivity depending on the substitution pattern of the aromatic compound. 
8. Predict products for simple pericyclic reactions.
9. Explain the mechanisms of radical reactions.
10. Develop short syntheses of target molecules.

SELF PACED DESIGN

On the course start date, students will have access to orientation. This must be completed to be able to gain access to the first module in the course. Students must complete the first module to gain access to the next one. We recommend that students spend about 15 hours per week to complete a course in 16 weeks. When trying to complete the course in less than 16 weeks, we typically see students do this successfully within 12-14 weeks. Instructors will be timely in grading and feedback, but it will not be instant.

Assignments

Worksheets

Each week, you will explore the new topics through the readings, videos, and worksheets. The worksheets are a place for you to take notes, draw, and try to answer problems. The materials are designed to help you walk through key ideas for the week. You can read the texts or watch the videos or play a game while you are doing the worksheets. You might find it effective to move back and forth between these activities. In fact, some of the videos will work through examples in the worksheets! Research shows that active engagement can increase your understanding and retention of the materials. To that end, you are strongly encouraged to print each week’s guided worksheets out first to have them on-hand while reading or viewing the learning materials. As they are a form of practice and engagement, you will receive points for completion alone.  If you are not understanding a topic through these materials, please contact the instructor!

Achieve Homework 

Each week, you will complete one or two short homework assignments in the Achieve system.  These homework assignments will be a chance for you to assess your understanding of the key concepts covered during that week.

In these activities, you can view hints without being penalized. You are also able to attempt each question multiple times, but be aware that you will receive a small penalty (5%) for each attempt after your first.  Note that you can compare your attempts to chart your progress with a question and review your work. Finally, be sure to review the feedback that you receive to better understand the correct responses.  You will be able to see the correct answer after you have submitted your assignment.

Achieve Quizzes

You will complete four shorter quizzes in the Achieve platform. These quizzes will be 20 questions and you will have 45 minutes to complete each one. Each quiz will be worth 20 points. They will usually cover 2-3 weeks of material and will ensure that you are retaining the material as we progress through the semester.

Discussion Boards

There will be four discussion boards this semester. There is an introductory board to foster a sense of community. There will be two discussion boards on topics of metacognition (how to study and learn). The last discussion board will involve a project on the impact that organic synthesis has had on society.

Activities

There are six activities in this course (and one optional extra credit activity!). These activities will ask you to apply the knowledge that you are learning. One assignment will involve you recording a description of a reaction mechanism. The “roadmaps” will ask you to help provide reagents for the synthesis of a target molecule. The synthesis projects are an opportunity to design your own roadmap to a target molecule. There is also one assignment in which you will summarize the content from the previous class into a table.  

Midterm Exams

You will complete two mid-term exams in the Achieve platform. These quizzes will be worth 50 points each. The exams will be 25 questions and you will have 60 minutes to complete them. You will have two exam attempts with the highest score being kept. They will usually cover 3-5 weeks of material and will ensure that you are retaining the material as we progress through the semester.

Final Exam

This will be a cumulative exam.  It will be a timed and proctored exam. There will be approximately 50 questions.  You will have 90 minutes to complete the exam and you may use the official UNE whiteboard. You will have two exam attempts with the highest score being kept. This assignment is worth 100 points toward your final grade.

This exam must be taken through ProctorU. See UNE’s Online ProctorU Site for information about signing up and scheduling your exam. A UNE-Compliant External Webcam is required (see the Course Materials section, above, for more information).

For proctored finals, grades will be posted 48-72 hours after taking the exams. 

Grading Policy

Your grade in this course will be determined by the following criteria:

Grade Breakdown

Assignment Category	Number of Assignments & Points	Total Point Values
Achieve Homework	12 x 10 pts, 5 x 5 pts	145 points
Achieve Quizzes	4 x 20 pts	80 points
Worksheets	13 x 5 pts	65 points
Discussions Boards	4 x 10 pts	40 points
Activities	Roadmap 1 (10 pts) Roadmap 2 (20 pts) Summary (5 pts) Mechanism (20 pts) Synthesis 1 (20 pts) Synthesis 2 (10 pts)	85 points
Midterm Exams	2 x 50 pts	100 points
Final Exam	1 x 100 pts	100 points
Total		615 points

Grade Scale

Grade	Points Grade	Point Average (GPA)
A	94 – 100%	4.00
A-	90 – 93%	3.75
B+	87 – 89%	3.50
B	84 – 86%	3.00
B-	80 – 83%	2.75
C+	77 – 79%	2.50
C	74 – 76%	2.00
C-	70 – 73%	1.75
D	64 – 69%	1.00
F	00 – 63%	0.00